SPERO THERAPEUTICS INC SPRO
$2.20
-0.9% 52w: $1.83 – $2.98
Latest 13F among current holders filed 1 month ago (Jul 15, 2026)
Price — last 12 months
research preview data1.832.412.98
Aug 18, 2025 Jul 2, 2026
Institutional holders
50
-6 QoQ
13F value
$49.3M
+0.1% QoQ
Smart-money holders
5
signal tier ≥ 2
New smart buyers
0
Q1 2026
Options barometer
0.6×
$194K calls / $350K puts
Institutional value by quarter
Number of holders
Who owns SPRO?
Q1 2026 filings| Fund | Type | Shares | Value | % of fund | Change |
|---|---|---|---|---|---|
| GSK plc ★3 | Fundamental concentrated | 9.2M | $21.5M | — | Held |
| Pfizer Inc ★3 | Fundamental concentrated | 2.4M | $5.5M | — | Held |
| VANGUARD CAPITAL MANAGEMENT LLC | Diversified mechanical | 1.8M | $4.2M | — | — |
| RENAISSANCE TECHNOLOGIES LLC | Quant stat arb | 1.2M | $2.8M | — | -7.1% |
| Alphabet Inc. ★3 | Fundamental concentrated | 890.0K | $2.1M | — | Held |
| TWO SIGMA INVESTMENTS, LP | Quant stat arb | 885.6K | $2.1M | 0.0% | +137.7% |
| Anson Funds Management LP | Quant stat arb | 843.9K | $2.0M | — | +35.0% |
| GEODE CAPITAL MANAGEMENT, LLC | Index provider | 519.9K | $1.2M | — | -1.8% |
| BlackRock, Inc. | Index provider | 433.2K | $1.0M | 0.0% | -0.1% |
| CITADEL ADVISORS LLC | Multistrat pod | 376.5K | $881K | 0.0% | -5.4% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Market maker | 333.1K | $779K | 0.0% | +13.4% |
| GSA CAPITAL PARTNERS LLP | Diversified mechanical | 278.3K | $651K | — | +55.5% |
| VANGUARD FIDUCIARY TRUST CO | Diversified mechanical | 264.1K | $618K | — | — |
| STATE STREET CORP | Index provider | 214.8K | $503K | 0.0% | +2.2% |
| Ionic Capital Management LLC ★2 | Fundamental diversified | 195.9K | $458K | — | Held |
| Squarepoint Ops LLC | Quant stat arb | 194.3K | $455K | 0.0% | +62.7% |
| MARSHALL WACE, LLP | Quant stat arb | 157.1K | $368K | — | New |
| NORTHERN TRUST CORP | Index provider | 121.0K | $283K | 0.0% | Held |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Diversified mechanical | 114.8K | $269K | — | Held |
| JANE STREET GROUP, LLC | Market maker | 106.3K | $249K | 0.0% | -32.8% |
| Shay Capital LLC | Quant stat arb | 70.4K | $165K | 0.0% | +16.7% |
| Point72 Asset Management, L.P. | Multistrat pod | 59.7K | $140K | 0.0% | +36.9% |
| Invesco Ltd. | Index provider | 45.4K | $106K | 0.0% | +83.7% |
| Quadrature Capital Ltd | Diversified mechanical | 40.1K | $94K | — | +6.2% |
| Capital Asset Advisory Services LLC | Wealth advisor | 32.5K | $92K | 0.0% | Held |
| OMERS ADMINISTRATION Corp | Other | 39.4K | $92K | 0.0% | -70.0% |
| Verdad Advisers, LP | Quant stat arb | 33.5K | $78K | — | New |
| SIMPLEX TRADING, LLC | Market maker | 30.3K | $71K | 0.0% | -15.1% |
| Three Seasons Wealth, LLC | Wealth advisor | 30.0K | $70K | 0.0% | Held |
| DIMENSIONAL FUND ADVISORS LP | Quant stat arb | 29.8K | $69K | — | Held |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | Index provider | 28.6K | $67K | — | Held |
| Vanguard Global Advisers, LLC | Diversified mechanical | 25.4K | $60K | — | — |
| Schonfeld Strategic Advisors LLC | Multistrat pod | 20.3K | $48K | 0.0% | New |
| CITIGROUP INC | Bank broker | 19.1K | $45K | 0.0% | +112458.8% |
| Assenagon Asset Management S.A. | Diversified mechanical | 18.6K | $44K | — | Held |
| OCCUDO QUANTITATIVE STRATEGIES LP | Quant stat arb | 16.4K | $41K | — | New |
| INTREPID FAMILY OFFICE LLC | Wealth advisor | 16.3K | $38K | — | -90.1% |
| Torrey Growth & Income Advisors ★2 | Fundamental diversified | 17.0K | $38K | 0.0% | Held |
| JONES FINANCIAL COMPANIES LLLP | Wealth advisor | 7.7K | $18K | 0.0% | +18.5% |
| FNY Investment Advisers, LLC | Quant stat arb | 5.3K | $12K | — | Held |
| MORGAN STANLEY | Bank broker | 4.6K | $11K | 0.0% | +1354.3% |
| UBS Group AG | Bank broker | 3.0K | $7K | 0.0% | -97.4% |
| OSAIC HOLDINGS, INC. | Wealth advisor | 290 | $678 | 0.0% | Held |
| JPMORGAN CHASE & CO | Bank broker | 236 | $529 | 0.0% | -95.6% |
| WELLS FARGO & COMPANY/MN | Bank broker | 200 | $468 | 0.0% | Held |
| US BANCORP \DE\ | Wealth advisor | 151 | $353 | 0.0% | Held |
| BNP PARIBAS FINANCIAL MARKETS | Bank broker | 40 | $94 | 0.0% | Held |
| Farther Finance Advisors, LLC | Wealth advisor | 10 | $25 | 0.0% | Held |
| SBI Securities Co., Ltd. | Diversified mechanical | 9 | $21 | 0.0% | Held |
| Caitong International Asset Management Co., Ltd | Diversified mechanical | 3 | $7 | — | New |
Exits are not a bearish signal: our backtest shows stocks specialists exit keep outperforming for 3+ quarters — selling usually means profit-taking, not a forecast.
Explore related
Top funds holding SPRO
More healthcare stocks held by institutions