Medicxi Ventures Management (Jersey) Ltd

Fundamental diversified ★Signal healthcare specialist (100%) CIK 1715579
Long book
$981.8M
Q1 2026
Positions
4
Top-10 weight
100%
concentration
Last quarter
+6.0%
SPY +14.8%
Turnover
20%
of book per quarter

Strategy in plain words

auto-generated from filings

Medicxi Ventures Management (Jersey) Ltd is a diversified fundamental manager, specialised in healthcare (100% of the long book), running a $981.8M US long book across 4 positions.

The portfolio is extremely concentrated — the top 10 positions are almost the whole book. Turnover is modest: positions are typically held for years. Current anchor positions: CENTESSA PHARMACEUTICALS-ADR, NEWAMSTERDAM PHARMA CO NV, PHATHOM PHARMACEUTICALS INC, AURA BIOSCIENCES INC.

Over the last 9 quarters its long book ran on average 0.2pp per quarter ahead of the S&P 500, beating the index in 4 of 9 quarters. We rate its filings as signal-bearing: position changes reflect genuine views.

Implied long-book return vs S&P 500

methodology: positions priced quarterly, no shorts/options
Fund long book S&P 500
Q1 2024
-9.4%
Q2 2024
+35.3%
Q3 2024
-24.0%
Q4 2024
-22.6%
Q1 2025
+15.6%
Q2 2025
+32.0%
Q3 2025
+28.1%
Q4 2025
-19.1%
Q1 2026
+6.0%

Sector allocation

Healthcare
100%

Long book by quarter

$449.2M
Q1 2024
$335.3M
Q2 2024
$528.9M
Q3 2024
$529.0M
Q4 2024
$437.7M
Q1 2025
$427.3M
Q2 2025
$744.4M
Q3 2025
$835.0M
Q4 2025
$981.8M
Q1 2026

What does Medicxi Ventures own?

Q1 2026 13F
CompanySectorSharesValue% of bookChange
NAMS NEWAMSTERDAM PHARMA CO NVHealthcare2.7M$85.6M8.7%-6.8%
PHAT PHATHOM PHARMACEUTICALS INCHealthcare7.5M$82.9M8.4%Held
AURA AURA BIOSCIENCES INCHealthcare3.0M$20.3M2.1%Held

13F filing history

PeriodFormFiledEntriesReported valueFlagsSource
Q1 202613F-HRApr 21, 20264$981.8M canonicalSEC ↗
Q4 202513F-HRJan 23, 20265$835.0M canonicalSEC ↗
Q3 202513F-HROct 17, 20255$744.4M canonicalSEC ↗
Q2 202513F-HRJul 8, 20255$427.3M canonicalSEC ↗
Q1 202513F-HRApr 11, 20255$437.7M canonicalSEC ↗
Q4 202413F-HRJan 23, 20255$529.0M canonicalSEC ↗
Q3 202413F-HROct 15, 20244$528.9M canonicalSEC ↗
Q2 202413F-HRJul 16, 20244$335.3M canonicalSEC ↗
Q1 202413F-HRApr 15, 20245$449.2M canonicalSEC ↗