Merck & Co., Inc.

Fundamental concentrated ★Highest signal healthcare specialist (100%) CIK 310158
League rank
#20
in Fundamental concentrated · #21 overall
Long book
$349.4M
Q1 2026
Positions
14
Top-10 weight
100%
concentration
Last quarter
+59.1%
SPY +14.8%
Turnover
27%
of book per quarter

Strategy in plain words

auto-generated from filings

Merck & Co., Inc. is a concentrated fundamental stock-picker, specialised in healthcare (100% of the long book), running a $349.4M US long book across 14 positions.

The portfolio is extremely concentrated — the top 10 positions are almost the whole book. The portfolio is actively managed, with meaningful quarterly turnover. Current anchor positions: MODERNA INC, PERSONALIS INC, KYMERA THERAPEUTICS INC, ENTRADA THERAPEUTICS INC, EIKON THERAPEUTICS INC.

Over the last 6 quarters its long book ran on average 11.3pp per quarter ahead of the S&P 500, beating the index in 4 of 6 quarters. We rate its filings highest-signal: new buys here are worth attention.

Implied long-book return vs S&P 500

methodology: positions priced quarterly, no shorts/options
Fund long book S&P 500
Q4 2024
-35.9%
Q1 2025
+31.9%
Q2 2025
+4.8%
Q3 2025
+22.2%
Q4 2025
+13.6%
Q1 2026
+59.1%

Sector allocation

Healthcare
100%
Other
0%

Long book by quarter

$258.0M
Q4 2024
$164.3M
Q1 2025
$215.6M
Q2 2025
$228.0M
Q3 2025
$276.3M
Q4 2025
$349.4M
Q1 2026

What does Merck & own?

Q1 2026 13F
CompanySectorSharesValue% of bookChange
MRNA MODERNA INCHealthcare2.3M$117.3M33.6%Held
PSNL PERSONALIS INCHealthcare14.0M$89.5M25.6%Held
KYMR KYMERA THERAPEUTICS INCHealthcare772.2K$64.3M18.4%Held
TRDA ENTRADA THERAPEUTICS INCHealthcare1.7M$22.0M6.3%Held
EIKN EIKON THERAPEUTICS INCHealthcare1.7M$17.6M5.0%New
AKTS AKTIS ONCOLOGY INCHealthcare952.8K$17.0M4.9%New
ALEC ALECTOR INCHealthcare3.5M$7.6M2.2%Held
VRDN VIRIDIAN THERAPEUTICS INCHealthcare93.4K$1.8M0.5%Held
XLO XILIO THERAPEUTICS INCHealthcare106.0K$891K0.3%New
CARM CARISMA THERAPEUTICS INC1.5M$48K0.0%Held
NEUP NEUPHORIA THERAPEUTICS INCHealthcare10.0K$41K0.0%Held
HURA TUHURA BIOSCIENCES INCHealthcare19.4K$35K0.0%+39.4%

13F filing history

PeriodFormFiledEntriesReported valueFlagsSource
Q1 202613F-HRMay 13, 202614$349.4M canonicalSEC ↗
Q4 202513F-HRFeb 17, 202612$276.3M canonicalSEC ↗
Q3 202513F-HRNov 12, 202513$228.0M canonicalSEC ↗
Q2 202513F-HRAug 13, 202513$215.6M canonicalSEC ↗
Q1 202513F-HRMay 14, 202512$164.3M canonicalSEC ↗
Q4 202413F-HRFeb 14, 202513$258.0M canonicalSEC ↗