NEXTBio Capital Management LP

Fundamental concentrated ★Highest signal healthcare specialist (100%) CIK 2038158
League rank
#473
in Fundamental concentrated · #1590 overall
Long book
$215.4M
Q1 2026
Positions
24
Top-10 weight
71%
concentration
Last quarter
+15.0%
SPY +14.8%
Turnover
4%
of book per quarter

Strategy in plain words

auto-generated from filings

NEXTBio Capital Management LP is a concentrated fundamental stock-picker, specialised in healthcare (100% of the long book), running a $215.4M US long book across 24 positions.

The portfolio is concentrated: the top 10 names carry 71% of the portfolio. The book barely moves quarter to quarter — a patient, low-turnover holder. Current anchor positions: TERNS PHARMACEUTICALS INC, PROTAGONIST THERAPEUTICS INC, SHATTUCK LABS INC, VOR BIOPHARMA INC, COMPASS PATHWAYS PLC.

We rate its filings highest-signal: new buys here are worth attention.

Implied long-book return vs S&P 500

methodology: positions priced quarterly, no shorts/options
Fund long book S&P 500
Q4 2025
+12.4%
Q1 2026
+15.0%

Sector allocation

Healthcare
82%
Other
18%

Long book by quarter

$170.5M
Q4 2025
$215.4M
Q1 2026

What does NEXTBio Capital own?

Q1 2026 13F
CompanySectorSharesValue% of bookChange
430 TERNS PHARMACEUTICALS INC604.5K$31.9M14.8%+9.7%
PTGX PROTAGONIST THERAPEUTICS INCHealthcare229.6K$24.2M11.2%Held
STTK SHATTUCK LABS INCHealthcare3.1M$20.3M9.4%Held
VOR VOR BIOPHARMA INCHealthcare1000.0K$17.8M8.3%Held
RYTM RHYTHM PHARMACEUTICALS INCHealthcare126.1K$11.0M5.1%+86.5%
XENE XENON PHARMACEUTICALS INCHealthcare183.2K$10.7M4.9%-0.3%
PVLA PALVELLA THERAPEUTICS INCHealthcare82.7K$10.3M4.8%Held
ZBIO ZENAS BIOPHARMA INCHealthcare426.7K$8.3M3.9%+32.5%
VSTM VERASTEM INCHealthcare1.3M$6.9M3.2%0.0%
CBIO CRESCENT BIOPHARMA INCHealthcare372.9K$6.8M3.2%Held
ORIC ORIC PHARMACEUTICALS INCHealthcare523.6K$6.6M3.1%-15.0%
PCVX VAXCYTE INCHealthcare95.2K$5.5M2.6%-0.3%
COGT COGENT BIOSCIENCES INCHealthcare131.2K$5.0M2.3%+36.9%
CMPX COMPASS THERAPEUTICS INCHealthcare848.2K$4.5M2.1%-23.9%
EVMN EVOMMUNE INCHealthcare184.1K$4.2M2.0%-19.4%
OCS OCULIS HOLDING AGHealthcare149.6K$4.0M1.8%-0.1%
IRON DISC MEDICINE INCHealthcare52.7K$3.4M1.6%+23.1%
4XC1 KALVISTA PHARMACEUTICALS INC131.8K$2.7M1.2%Held
SMMT SUMMIT THERAPEUTICS INCHealthcare89.7K$1.7M0.8%New
ACET ADICET BIO INCHealthcare157.8K$1.1M0.5%Held

13F filing history

PeriodFormFiledEntriesReported valueFlagsSource
Q1 202613F-HRMay 14, 202624$215.4M canonicalSEC ↗
Q4 202513F-HRFeb 13, 202623$170.5M canonicalSEC ↗