Syncona Portfolio Ltd
Long book
$25.7M
Q1 2026
Positions
2
Top-10 weight
100%
concentration
Last quarter
+13.7%
SPY +14.8%
Turnover
0%
of book per quarter
Strategy in plain words
auto-generated from filingsSyncona Portfolio Ltd is a diversified fundamental manager, specialised in healthcare (100% of the long book), running a $25.7M US long book across 2 positions.
The portfolio is extremely concentrated — the top 10 positions are almost the whole book. The book barely moves quarter to quarter — a patient, low-turnover holder. Current anchor positions: AUTOLUS THERAPEUTICS PLC, CENTURY THERAPEUTICS INC.
Over the last 9 quarters its long book ran on average 13.6pp per quarter behind the S&P 500, beating the index in 2 of 9 quarters. We rate its filings as signal-bearing: position changes reflect genuine views.
Implied long-book return vs S&P 500
methodology: positions priced quarterly, no shorts/options Fund long book S&P 500
Q1 2024
-45.5%
Q2 2024
+3.1%
Q3 2024
-35.4%
Q4 2024
-34.6%
Q1 2025
+46.4%
Q2 2025
-28.2%
Q3 2025
+23.8%
Q4 2025
-25.1%
Q1 2026
+13.7%
Sector allocation
Healthcare 100%
Long book by quarter
What does Syncona Portfolio own?
Q1 2026 13F| Company | Sector | Shares | Value | % of book | Change |
|---|---|---|---|---|---|
| IPSC CENTURY THERAPEUTICS INC | Healthcare | 1.2M | $2.7M | 10.7% | Held |
13F filing history
| Period | Form | Filed | Entries | Reported value | Flags | Source |
|---|---|---|---|---|---|---|
| Q1 2026 | 13F-HR | May 14, 2026 | 2 | $25.7M | canonical | SEC ↗ |
| Q4 2025 | 13F-HR | Feb 5, 2026 | 2 | $34.3M | canonical | SEC ↗ |
| Q3 2025 | 13F-HR | Nov 6, 2025 | 2 | $27.7M | canonical | SEC ↗ |
| Q2 2025 | 13F-HR | Aug 7, 2025 | 2 | $38.6M | canonical | SEC ↗ |
| Q1 2025 | 13F-HR | May 7, 2025 | 3 | $26.4M | canonical | SEC ↗ |
| Q4 2024 | 13F-HR | Feb 6, 2025 | 3 | $53.0M | canonical | SEC ↗ |
| Q3 2024 | 13F-HR | Nov 14, 2024 | 3 | $80.7M | canonical | SEC ↗ |
| Q2 2024 | 13F-HR | Aug 13, 2024 | 3 | $85.9M | canonical | SEC ↗ |
| Q1 2024 | 13F-HR | May 7, 2024 | 2 | $150.1M | canonical | SEC ↗ |