TRV GP V, LLC

Fundamental diversified ★Signal healthcare specialist (100%) CIK 1990717
Long book
$401.0M
Q1 2026
Positions
3
Top-10 weight
100%
concentration
Last quarter
+29.5%
SPY +14.8%
Turnover
0%
of book per quarter

Strategy in plain words

auto-generated from filings

TRV GP V, LLC is a diversified fundamental manager, specialised in healthcare (100% of the long book), running a $401.0M US long book across 3 positions.

The portfolio is extremely concentrated — the top 10 positions are almost the whole book. The book barely moves quarter to quarter — a patient, low-turnover holder. Current anchor positions: RAPPORT THERAPEUTICS INC, SEPTERNA INC, MAZE THERAPEUTICS INC.

Over the last 6 quarters its long book ran on average 19pp per quarter ahead of the S&P 500, beating the index in 4 of 6 quarters. We rate its filings as signal-bearing: position changes reflect genuine views.

Implied long-book return vs S&P 500

methodology: positions priced quarterly, no shorts/options
Fund long book S&P 500
Q4 2024
-60.0%
Q1 2025
+34.3%
Q2 2025
+123.0%
Q3 2025
+21.4%
Q4 2025
-6.6%
Q1 2026
+29.5%

Sector allocation

Healthcare
100%

Long book by quarter

$294.0M
Q4 2024
$125.1M
Q1 2025
$165.7M
Q2 2025
$353.5M
Q3 2025
$429.2M
Q4 2025
$401.0M
Q1 2026

What does TRV GP own?

Q1 2026 13F
CompanySectorSharesValue% of bookChange
RAPP RAPPORT THERAPEUTICS INCHealthcare7.1M$223.3M55.7%Held
SEPN SEPTERNA INCHealthcare6.2M$149.4M37.2%Held
MAZE MAZE THERAPEUTICS INCHealthcare950.8K$28.4M7.1%Held

13F filing history

PeriodFormFiledEntriesReported valueFlagsSource
Q1 202613F-HRMay 7, 20263$401.0M canonicalSEC ↗
Q4 202513F-HRFeb 13, 20263$429.2M canonicalSEC ↗
Q3 202513F-HRNov 13, 20253$353.5M canonicalSEC ↗
Q2 202513F-HRAug 8, 20254$165.7M canonicalSEC ↗
Q1 202513F-HRMay 9, 20254$125.1M canonicalSEC ↗
Q4 202413F-HRFeb 13, 20253$294.0M canonicalSEC ↗