TRV GP VI, LLC

Fundamental diversified ★Signal healthcare specialist (100%) CIK 1990716
Long book
$135.6M
Q1 2026
Positions
3
Top-10 weight
100%
concentration
Last quarter
+37.7%
SPY +14.8%
Turnover
0%
of book per quarter

Strategy in plain words

auto-generated from filings

TRV GP VI, LLC is a diversified fundamental manager, specialised in healthcare (100% of the long book), running a $135.6M US long book across 3 positions.

The portfolio is extremely concentrated — the top 10 positions are almost the whole book. The book barely moves quarter to quarter — a patient, low-turnover holder. Current anchor positions: SEPTERNA INC, RAPPORT THERAPEUTICS INC, TANGO THERAPEUTICS INC.

Over the last 6 quarters its long book ran on average 21.1pp per quarter ahead of the S&P 500, beating the index in 4 of 6 quarters. We rate its filings as signal-bearing: position changes reflect genuine views.

Implied long-book return vs S&P 500

methodology: positions priced quarterly, no shorts/options
Fund long book S&P 500
Q4 2024
-68.6%
Q1 2025
+64.5%
Q2 2025
+93.9%
Q3 2025
+35.5%
Q4 2025
-8.7%
Q1 2026
+37.7%

Sector allocation

Healthcare
100%

Long book by quarter

$116.9M
Q4 2024
$42.0M
Q1 2025
$64.2M
Q2 2025
$109.6M
Q3 2025
$148.5M
Q4 2025
$135.6M
Q1 2026

What does TRV GP own?

Q1 2026 13F
CompanySectorSharesValue% of bookChange
SEPN SEPTERNA INCHealthcare4.2M$101.2M74.6%Held
RAPP RAPPORT THERAPEUTICS INCHealthcare969.2K$30.3M22.4%Held
TNGX TANGO THERAPEUTICS INCHealthcare194.2K$4.1M3.0%Held

13F filing history

PeriodFormFiledEntriesReported valueFlagsSource
Q1 202613F-HRMay 7, 20263$135.6M canonicalSEC ↗
Q4 202513F-HRFeb 13, 20263$148.5M canonicalSEC ↗
Q3 202513F-HRNov 13, 20253$109.6M canonicalSEC ↗
Q2 202513F-HRAug 8, 20254$64.2M canonicalSEC ↗
Q1 202513F-HRMay 9, 20254$42.0M canonicalSEC ↗
Q4 202413F-HRFeb 13, 20254$116.9M canonicalSEC ↗