IONIS PHARMACEUTICALS INC IONS
$81.80
+3.3% 52w: $41.82 – $86.50
Latest 13F among current holders filed 5 days ago (Aug 28, 2026)
Price — last 12 months
research preview data41.8264.1686.50
Aug 18, 2025 Jul 2, 2026
Institutional holders
497
+3 QoQ
13F value
$12.97B
-7.0% QoQ
Smart-money holders
34
signal tier ≥ 2
New smart buyers
8
Q1 2026
Options barometer
1.0×
$141.4M calls / $144.3M puts
Institutional value by quarter
Number of holders
Who owns IONS?
Q1 2026 filings| Fund | Type | Shares | Value | % of fund | Change |
|---|---|---|---|---|---|
| FMR LLC | Long only active | 24.6M | $1.84B | 0.1% | +2.0% |
| Capital World Investors | Long only active | 21.2M | $1.59B | 0.2% | +18.0% |
| BlackRock, Inc. | Index provider | 10.4M | $784.1M | 0.0% | -1.9% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Diversified mechanical | 7.8M | $586.4M | — | — |
| VANGUARD CAPITAL MANAGEMENT LLC | Diversified mechanical | 7.1M | $534.5M | — | — |
| WELLINGTON MANAGEMENT GROUP LLP | Long only active | 6.4M | $480.0M | 0.1% | +2.1% |
| T. Rowe Price Investment Management, Inc. | Long only active | 6.2M | $462.5M | — | -58.7% |
| TWO SIGMA INVESTMENTS, LP | Quant stat arb | 5.9M | $439.8M | 0.4% | +120.3% |
| GEODE CAPITAL MANAGEMENT, LLC | Index provider | 4.0M | $305.2M | — | +26.5% |
| STATE STREET CORP | Index provider | 4.0M | $300.0M | 0.0% | +0.5% |
| ROYAL BANK OF CANADA | Bank broker | 3.8M | $285.5M | 0.1% | +239.8% |
| PRICE T ROWE ASSOCIATES INC /MD/ | Diversified mechanical | 3.0M | $227.2M | 0.0% | +1.3% |
| JPMORGAN CHASE & CO | Bank broker | 2.4M | $171.4M | 0.0% | +2.6% |
| Tweedy, Browne Co LLC ★2 | Fundamental diversified | 2.3M | $170.9M | — | -7.7% |
| Artisan Partners Limited Partnership | Other | 2.1M | $154.6M | — | +74.2% |
| BAKER BROS. ADVISORS LP ★2 | Fundamental diversified | 2.0M | $153.8M | — | +14.3% |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Quant stat arb | 2.0M | $148.7M | — | Held |
| Deep Track Capital, LP ★2 | Fundamental diversified | 1.9M | $146.4M | — | +14.7% |
| Bellevue Group AG ★2 | Fundamental diversified | 1.8M | $136.6M | 3.2% | -62.1% |
| GOLDMAN SACHS GROUP INC | Bank broker | 1.7M | $127.6M | 0.0% | +98.6% |
| AMERICAN CENTURY COMPANIES INC | Diversified mechanical | 1.7M | $124.9M | — | +2.9% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | Index provider | 1.6M | $118.9M | — | +2.7% |
| FRANKLIN RESOURCES INC | Long only active | 1.6M | $118.3M | 0.0% | +19.2% |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Bank broker | 1.5M | $110.8M | 0.0% | +6.3% |
| Pictet Asset Management Holding SA | Diversified mechanical | 1.4M | $107.1M | — | +1.2% |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC ★2 | Fundamental diversified | 1.4M | $105.4M | — | -4.0% |
| Invesco Ltd. | Index provider | 1.3M | $95.9M | 0.0% | +0.6% |
| MILLENNIUM MANAGEMENT LLC | Multistrat pod | 1.1M | $79.0M | 0.1% | +1027.5% |
| MORGAN STANLEY | Bank broker | 1.0M | $77.1M | 0.0% | +0.6% |
| VANGUARD FIDUCIARY TRUST CO | Diversified mechanical | 1.0M | $76.9M | — | — |
| CITADEL ADVISORS LLC | Multistrat pod | 942.5K | $70.8M | 0.1% | -55.8% |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Bank broker | 907.5K | $68.1M | 0.1% | -32.9% |
| Connor, Clark & Lunn Investment Management Ltd. | Diversified mechanical | 874.1K | $65.6M | — | -18.8% |
| NORTHERN TRUST CORP | Index provider | 868.2K | $65.2M | 0.0% | +2.5% |
| BANK OF AMERICA CORP /DE/ | Bank broker | 840.6K | $63.1M | 0.0% | +7.3% |
| Polar Capital Holdings Plc | Other | 829.5K | $62.3M | — | -37.8% |
| GROUPAMA ASSET MANAGMENT | Other | 824.5K | $61.9M | — | +7.5% |
| UBS Group AG | Bank broker | 808.4K | $60.7M | 0.0% | -22.6% |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | Diversified mechanical | 785.3K | $59.0M | — | -9.2% |
| GW&K Investment Management, LLC | Other | 779.3K | $58.5M | 0.5% | -0.9% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | Quant stat arb | 737.9K | $55.4M | 0.0% | -30.6% |
| Squarepoint Ops LLC | Quant stat arb | 695.3K | $52.2M | 0.1% | +59.4% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Diversified mechanical | 672.9K | $50.5M | — | +15.0% |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Other | 666.1K | $50.0M | — | -18.0% |
| AMERIPRISE FINANCIAL INC | Bank broker | 660.1K | $49.6M | 0.0% | +10.3% |
| Nuveen, LLC | Diversified mechanical | 648.5K | $48.7M | 0.0% | -1.9% |
| Eversept Partners, LP ★2 | Fundamental diversified | 632.1K | $47.5M | — | +17.4% |
| EVENTIDE ASSET MANAGEMENT, LLC | Other | 575.0K | $43.2M | — | Held |
| TD Asset Management Inc | Diversified mechanical | 530.0K | $39.8M | 0.0% | -31.5% |
| TEACHER RETIREMENT SYSTEM OF TEXAS | Diversified mechanical | 523.9K | $39.3M | — | +23.9% |
Exits are not a bearish signal: our backtest shows stocks specialists exit keep outperforming for 3+ quarters — selling usually means profit-taking, not a forecast.
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